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CELL\u6c5f\u5357\u9662\u4ee3\u8868\u9662\u957f\u91d1\u6e0a\u632f\uff08Dr. KIM 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Aesthetics\u57282023\u5e74\u5ba3\u5e03\uff0cSkinvive\u83b7\u5f97\u7f8e\u56fdFDA\u6279\u51c6\uff0c\u7528\u4e8e21\u5c81\u4ee5\u4e0a\u6210\u4eba\u7684\u9762\u988a\u76ae\u80a4\u5149\u6ed1\u5ea6\u6539\u5584\uff0c\u5e76\u8868\u793a\u5728\u6700\u4f73\u6ce8\u5c04\u6761\u4ef6\u4e0b\u6548\u679c\u53ef\u7ef4\u63016\u4e2a\u6708\u3002AbbVie\u57282026\u5e746\u6708\u53c8\u5ba3\u5e03\u4e86\u4e00\u9879\u65b0\u9002\u5e94\u75c7\u7684\u6279\u51c6\uff0c\u7528\u4e8e\u6539\u5584\u9888\u7eb9\u3002\u8fd9\u91cc\u7684\u201c6\u4e2a\u6708\u201d\u662f\u5382\u5546\u516c\u5e03\u7684\u7279\u5b9a\u4ea7\u54c1\u4e34\u5e8a\u7ed3\u679c\uff0c\u4e0d\u80fd\u76f4\u63a5\u5957\u7528\u5230\u6240\u6709\u540d\u5b57\u91cc\u5e26\u201c\u6c34\u5149\u201d\u4e8c\u5b57\u7684\u73bb\u5c3f\u9178\u6ce8\u5c04\u5242\u4e0a\u3002<\/p>\n<p>\u987a\u5e26\u4e00\u63d0\uff0c\u6211\u672c\u4eba\u662f\u4e54\u96c5\u767b\u4e0e\u8089\u6bd2\u4ea7\u54c1\u7684Allergan\u8ba4\u8bc1\u8bb2\u5e08\uff08faculty\uff09\u3002\u5728\u4ecb\u7ecd\u8fd9\u4e00\u7c7b\u4ea7\u54c1\u65f6\uff0c\u6211\u8ba4\u4e3a\u5e94\u8be5\u8ba9\u5927\u5bb6\u77e5\u9053\u8fd9\u4e00\u70b9\u3002<\/p>\n<p>\u75d5\u8ff9\u65b9\u9762\uff0cDermatology Times\u57282026\u5e74\u6574\u7406\u7684Skinvive\u9888\u7eb9\u9002\u5e94\u75c7\u4e34\u5e8a\u6570\u636e\u663e\u793a\uff0c\u6ce8\u5c04\u90e8\u4f4d\u53cd\u5e94\u5927\u591a\u8f7b\u5fae\uff0c\u5e76\u5728\u4e24\u5468\u5185\u6d88\u9000\u3002\u6d88\u9000\u6240\u9700\u65f6\u95f4\u56e0\u4eba\u800c\u5f02\uff0c\u51fa\u73b0\u6de4\u9752\u65f6\u53ef\u80fd\u6301\u7eed\u66f4\u4e45\uff0c\u56e0\u6b64\u628a\u6ce8\u5c04\u5b89\u6392\u5728\u505c\u7559\u521d\u671f\uff0c\u6bd4\u5b89\u6392\u5728\u51fa\u5883\u524d\u4e00\u5929\u66f4\u7a33\u59a5\u3002<\/p>\n<h2>\u4e3d\u73e0\u5170\uff08PN\u805a\u6838\u82f7\u9178\uff09\uff1a\u9760\u7597\u7a0b\u7d2f\u79ef\u7684\u76ae\u80a4\u808c\u7406<\/h2>\n<p>\u4e3d\u73e0\u5170\u9ed1\u76d2\u3001\u4e3d\u73e0\u5170\u7ea2\u76d2\uff08\u4e3d\u73e0\u5170HB+\uff09\u7b49\u4ea7\u54c1\u4ee5\u805a\u6838\u82f7\u9178\uff08PN\uff09\u4e3a\u4e3b\u8981\u6210\u5206\u3002\u4e00\u9879\u53d1\u8868\u4e8ePMC\u3001\u9488\u5bf9\u773c\u5468\u6ce8\u5c04\u7684\u524d\u77bb\u6027\u89c2\u5bdf\u7814\u7a76\uff0842\u4eba\uff09\u5728\u5f15\u8a00\u90e8\u5206\u8bf4\u660e\uff0cPN\u662f\u5206\u5b50\u91cf\u6bd4PDRN\u66f4\u5927\u7684\u5f62\u6001\uff0c\u9ecf\u7a20\u5ea6\u66f4\u9ad8\uff0c\u6548\u679c\u4e5f\u76f8\u5e94\u66f4\u6301\u4e45\u3002\u540c\u4e00\u7814\u7a76\u663e\u793a\uff0c\u5b8c\u62102\u6b21\u7597\u7a0b\u540e\u7684\u7b2c3\u4e2a\u6708\uff0c\u6539\u5584\u7a0b\u5ea6\u4e0e\u6ee1\u610f\u5ea6\u8fbe\u5230\u5cf0\u503c\uff0c\u7b2c6\u4e2a\u6708\u65f6\u6539\u5584\u4ecd\u7136\u4fdd\u6301\u3002<\/p>\n<p>\u7597\u7a0b\u95f4\u9694\u53ef\u4ee5\u53c2\u8003\u56fd\u5185\u8bca\u7597\u73b0\u573a\u7684\u4e60\u60ef\u3002Rho\u7b49\u7814\u7a76\u8005\u5728\u300a\u7f8e\u5bb9\u76ae\u80a4\u75c5\u5b66\u6742\u5fd7\u300b\uff08Journal of Cosmetic Dermatology\uff0c2024\u5e74\uff09\u53d1\u8868\u7684\u8c03\u67e5\u4e2d\uff0c235\u540d\u719f\u6089\u76ae\u80a4\u586b\u5145\u7c7b\u4ea7\u54c1\u7684\u97e9\u56fd\u76ae\u80a4\u79d1\u533b\u751f\u53c2\u4e0e\u4e86\u95ee\u5377\u3002\u7ed3\u679c\u663e\u793a\uff0c\u56fd\u5185\u6700\u5e38\u4f7f\u7528\u7684\u76ae\u80a4\u586b\u5145\u4ea7\u54c1\u662f\u6ce8\u5c04\u578bPN\uff0c\u6700\u5e38\u88ab\u63a8\u8350\u7684\u65b9\u6848\u662f\u95f4\u96944\u5468\u3001\u51713\u6b21\u3002\u53d7\u8bbf\u533b\u751f\u8ba4\u4e3aPN\u6700\u9002\u5408\u7684\u9002\u5e94\u75c7\u662f\u9762\u90e8\u7ec6\u7eb9\u3002<\/p>\n<p>\u6240\u4ee5\u5982\u679c\u628a\u4e3d\u73e0\u5170\u5f53\u6210\u201c\u6253\u4e00\u6b21\u9a6c\u4e0a\u51fa\u5149\u201d\u7684\u6ce8\u5c04\uff0c\u5bb9\u6613\u5931\u671b\u3002\u7b2c\u4e00\u6b21\u7597\u7a0b\u53ea\u662f\u8d77\u70b9\uff0c\u6548\u679c\u9700\u8981\u7528\u51e0\u5468\u5230\u51e0\u4e2a\u6708\u7684\u65f6\u95f4\u6765\u5224\u65ad\u3002<\/p>\n<p>\u75d5\u8ff9\u65b9\u9762\u6700\u5178\u578b\u7684\u662f\u5c0f\u9f13\u5305\u3002\u7531\u4e8e\u5236\u5242\u4ee5\u5c0f\u6db2\u6ef4\u7684\u5f62\u5f0f\u6ce8\u5165\u771f\u76ae\u5c42\uff0c\u6ce8\u5c04\u540e\u76ae\u80a4\u8868\u9762\u4f1a\u51fa\u73b0\u51f9\u51f8\u4e0d\u5e73\u7684\u75d5\u8ff9\u3002PMC\u516c\u5f00\u7684\u4e00\u9879\u773c\u5468PN\u957f\u671f\u5b89\u5168\u6027\u56de\u987e\u7814\u7a76\uff0823\u4eba\uff0c\u517191\u6b21\u6ce8\u5c04\uff09\u8bb0\u5f55\u52302\u6b21\u8f7b\u5fae\u4e0d\u826f\u53cd\u5e94\uff0c\u5176\u4e2d\u4e00\u4eba\u7684\u6ce8\u5c04\u75d5\u8ff9\u4e18\u75b9\u6301\u7eed\u4e86\u6700\u957f24\u5c0f\u65f6\u540e\u81ea\u884c\u6d88\u9000\u3002\u8fd9\u9879\u7814\u7a76\u9488\u5bf9\u7684\u662f\u773c\u5468\u8fd9\u4e00\u6709\u9650\u90e8\u4f4d\u7684\u5c0f\u6837\u672c\uff0c\u4e0d\u80fd\u76f4\u63a5\u5957\u7528\u5230\u5168\u8138\u6ce8\u5c04\u3002<\/p>\n<p>\u8bc1\u636e\u7684\u8fb9\u754c\u4e5f\u9700\u8981\u8bf4\u660e\u3002Lampridou S\u3001Bassett S\u3001Cavallini M\u3001Christopoulos G\u7b49\u7814\u7a76\u8005\u5728\u300a\u7f8e\u5bb9\u76ae\u80a4\u75c5\u5b66\u6742\u5fd7\u300b\uff082025\u5e74\uff09\u53d1\u8868\u7684\u7cfb\u7edf\u6027\u6587\u732e\u7efc\u8ff0\uff0c\u5728\u603b\u7ed3PN\u7684\u7f8e\u5bb9\u6548\u679c\u540e\u6307\u51fa\uff0c\u8fd9\u4e00\u9886\u57df\u4ecd\u9700\u8981\u66f4\u6807\u51c6\u5316\u7684\u7814\u7a76\u65b9\u6cd5\u3001\u66f4\u5927\u7684\u6837\u672c\u89c4\u6a21\u548c\u66f4\u957f\u7684\u968f\u8bbf\u65f6\u95f4\u3002\u65b9\u5411\u662f\u79ef\u6781\u7684\uff0c\u4f46\u201c\u7ef4\u6301\u51e0\u4e2a\u6708\u201d\u8fd9\u7c7b\u6570\u5b57\u5728\u4e0d\u540c\u7814\u7a76\u4e4b\u95f4\u7684\u6761\u4ef6\u5e76\u4e0d\u7edf\u4e00\u3002<\/p>\n<h2>\u5916\u6ccc\u4f53\u5e94\u8be5\u653e\u5728\u54ea\u4e2a\u4f4d\u7f6e\u770b\u5f85<\/h2>\n<p>\u5916\u6ccc\u4f53\u662f\u5229\u7528\u7ec6\u80de\u5206\u6ccc\u7684\u5fae\u5c0f\u56ca\u6ce1\u5236\u6210\u7684\u6750\u6599\u3002\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5728\u4e00\u4efd\u5173\u4e8e\u5e72\u7ec6\u80de\u4e0e\u5916\u6ccc\u4f53\u4ea7\u54c1\u7684\u516c\u5171\u5b89\u5168\u8b66\u793a\u4e2d\u8bf4\u660e\uff0c\u76ee\u524d\u6ca1\u6709\u4efb\u4f55\u5916\u6ccc\u4f53\u4ea7\u54c1\u83b7\u5f97FDA\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u75be\u75c5\u7684\u5916\u6ccc\u4f53\u5c5e\u4e8e\u836f\u54c1\u6216\u751f\u7269\u5236\u54c1\u76d1\u7ba1\u8303\u7574\u3002<\/p>\n<p>\u56e0\u6b64\u6211\u4e0d\u4f1a\u628a\u5916\u6ccc\u4f53\u548c\u524d\u9762\u4e24\u7c7b\u4ea7\u54c1\u5e76\u5217\u6bd4\u8f83\u201c\u7ef4\u6301\u51e0\u4e2a\u6708\u201d\u3002\u5982\u679c\u60a8\u5bf9\u8fd9\u7c7b\u4ea7\u54c1\u611f\u5174\u8da3\uff0c\u5efa\u8bae\u5728\u9762\u8bca\u65f6\u5148\u786e\u8ba4\u5b83\u5c5e\u4e8e\u54ea\u79cd\u76d1\u7ba1\u5206\u7c7b\uff0c\u4ee5\u53ca\u662f\u6d82\u62b9\u4f7f\u7528\u8fd8\u662f\u6ce8\u5c04\u4f7f\u7528\u3002<\/p>\n<h2>\u628a\u4e09\u8005\u653e\u5728\u540c\u4e00\u65f6\u95f4\u8f74\u4e0a\u6bd4\u8f83<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u7c7b\u522b<\/th>\n<th>\u4f5c\u7528\u65b9\u5f0f<\/th>\n<th>\u5149\u6cfd\u51fa\u73b0\u901f\u5ea6<\/th>\n<th>\u7ef4\u6301\u76f8\u5173\u62a5\u9053<\/th>\n<th>\u75d5\u8ff9\uff08\u6309\u6587\u732e\uff09<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u73bb\u5c3f\u9178\u6c34\u5149\u9488\uff08\u542bSkinvive\uff09<\/td>\n<td>\u9501\u6c34\u4f7f\u76ae\u80a4\u5149\u6ed1<\/td>\n<td>\u8f83\u5feb\uff08\u8865\u6c34\u4e0e\u586b\u5145\u6548\u679c\uff09<\/td>\n<td>Skinvive\uff1a\u6700\u4f73\u6761\u4ef6\u4e0b6\u4e2a\u6708\uff08\u5382\u5546\u516c\u5e03\uff09<\/td>\n<td>\u9888\u7eb9\u4e34\u5e8a\u4e2d\u6ce8\u5c04\u90e8\u4f4d\u53cd\u5e94\u591a\u57282\u5468\u5185\u6d88\u9000<\/td>\n<\/tr>\n<tr>\n<td>\u4e3d\u73e0\u5170\uff08PN\u5236\u5242\uff09<\/td>\n<td>\u6309\u7597\u7a0b\u7d2f\u79ef\u6539\u5584\u808c\u7406\u4e0e\u7ec6\u7eb9<\/td>\n<td>\u968f\u7597\u7a0b\u6b21\u6570\u9010\u6b65\u663e\u73b0<\/td>\n<td>\u773c\u5468\u7814\u7a76\uff1a2\u6b21\u540e\u7b2c3\u4e2a\u6708\u8fbe\u5cf0\u503c\uff0c\u7b2c6\u4e2a\u6708\u4ecd\u7ef4\u6301\uff1b\u56fd\u5185\u8c03\u67e5\u4e2d4\u5468\u95f4\u96943\u6b21\u4e3a\u6700\u5e38\u89c1\u63a8\u8350<\/td>\n<td>\u5c0f\u9f13\u5305\uff1b\u773c\u5468\u7814\u7a76\u4e2d\u4e18\u75b9\u6700\u957f\u6301\u7eed24\u5c0f\u65f6<\/td>\n<\/tr>\n<tr>\n<td>\u5916\u6ccc\u4f53<\/td>\n<td>\u5229\u7528\u7ec6\u80de\u5206\u6ccc\u56ca\u6ce1<\/td>\n<td>\u8bc1\u636e\u5c1a\u672a\u7cfb\u7edf\u6574\u7406<\/td>\n<td>\u5c1a\u65e0FDA\u6279\u51c6\u4ea7\u54c1<\/td>\n<td>\u56e0\u4ea7\u54c1\u5206\u7c7b\u4e0e\u4f7f\u7528\u65b9\u5f0f\u800c\u5f02<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u8868\u683c\u4e2d\u7684\u6570\u5b57\u5206\u522b\u6765\u81ea\u4e0d\u540c\u4ea7\u54c1\u3001\u4e0d\u540c\u90e8\u4f4d\u3001\u4e0d\u540c\u4eba\u6570\u7684\u7814\u7a76\u3002\u8fd9\u4e9b\u7814\u7a76\u5f7c\u6b64\u4e4b\u95f4\u6ca1\u6709\u76f4\u63a5\u5bf9\u7167\uff0c\u8bf7\u4e0d\u8981\u628a\u5b83\u4eec\u7406\u89e3\u6210\u67d0\u4e00\u7c7b\u6bd4\u53e6\u4e00\u7c7b\u957f\u51fa\u51e0\u500d\u3002<\/p>\n<h2>\u6309\u505c\u7559\u5929\u6570\u5236\u5b9a\u8ba1\u5212\u7684\u53c2\u8003<\/h2>\n<p>\u4ee5\u4e0b\u5b89\u6392\u662f\u6211\u6839\u636e\u4e0a\u8ff0\u8bc1\u636e\uff0c\u5728\u5236\u5b9a\u884c\u7a0b\u65f6\u4e60\u60ef\u91c7\u7528\u7684\u53c2\u8003\u539f\u5219\u3002\u5177\u4f53\u65b9\u6848\u4ecd\u9700\u9762\u8bca\u540e\u6839\u636e\u4e2a\u4eba\u76ae\u80a4\u72b6\u51b5\u51b3\u5b9a\u3002<\/p>\n<ul>\n<li><strong>\u505c\u75592\u52303\u5929<\/strong>\uff1a\u5982\u679c\u5e0c\u671b\u8fd9\u6b21\u65c5\u884c\u4e2d\u5c31\u770b\u5230\u5149\u6cfd\uff0c\u73bb\u5c3f\u9178\u7c7b\u6c34\u5149\u9488\u5b89\u63921\u6b21\u662f\u6bd4\u8f83\u73b0\u5b9e\u7684\u9009\u62e9\u3002\u5efa\u8bae\u653e\u5728\u62b5\u8fbe\u6b21\u65e5\u8fd9\u6837\u7684\u505c\u7559\u521d\u671f\uff0c\u7559\u51fa\u89c2\u5bdf\u6de4\u9752\u548c\u80bf\u80c0\u7684\u65f6\u95f4\u3002<\/li>\n<li><strong>\u505c\u75595\u52307\u5929<\/strong>\uff1a\u53ef\u4ee5\u4ee5\u73bb\u5c3f\u9178\u7c7b\u4e3a\u4e3b\uff0c\u4e5f\u53ef\u4ee5\u8003\u8651\u5f00\u59cb\u7b2c\u4e00\u6b21\u4e3d\u73e0\u5170\u7597\u7a0b\u5e76\u5728\u505c\u7559\u671f\u95f4\u89c2\u5bdf\u53d8\u5316\u3002\u5982\u679c\u9009\u62e9\u5f00\u59cbPN\u7597\u7a0b\uff0c\u53ef\u4ee5\u628a\u4e0b\u4e00\u6b21\u9884\u7ea6\u5f80\u540e\u63a8\u7b97\u7ea64\u5468\uff0c\u4e0e\u8c03\u67e5\u4e2d\u6700\u5e38\u89c1\u7684\u63a8\u8350\u95f4\u9694\u5bf9\u9f50\u3002<\/li>\n<li><strong>\u7ecf\u5e38\u5f80\u8fd4\u9996\u5c14\u7684\u60c5\u51b5<\/strong>\uff1a\u53ef\u4ee5\u63d0\u524d\u628aPN\u7597\u7a0b\u8ba1\u5212\uff08\u4f8b\u5982\u95f4\u96944\u5468\u51713\u6b21\uff09\u548c\u8bbf\u95ee\u884c\u7a0b\u5bf9\u9f50\uff0c\u8fd9\u6837\u66f4\u5bb9\u6613\u5224\u65ad\u6548\u679c\u3002<\/li>\n<\/ul>\n<p>\u65e0\u8bba\u9009\u62e9\u54ea\u79cd\u5b89\u6392\uff0c\u5982\u679c\u51fa\u5883\u5f53\u5929\u6709\u4e0d\u80fd\u7559\u4e0b\u5c0f\u9f13\u5305\u6216\u6de4\u9752\u7684\u5b89\u6392\uff0c\u6bd4\u5982\u673a\u573a\u62cd\u6444\u6216\u91cd\u8981\u4f1a\u9762\uff0c\u8bf7\u52a1\u5fc5\u5728\u9762\u8bca\u65f6\u63d0\u524d\u544a\u77e5\u3002\u8fd9\u4e00\u4e2a\u6761\u4ef6\uff0c\u6709\u65f6\u4f1a\u76f4\u63a5\u6539\u53d8\u4ea7\u54c1\u7c7b\u522b\u7684\u9009\u62e9\u3002<\/p>\n<h2>\u6c5f\u5357\u9662\u5185\u4ece\u6ce8\u5c04\u5230\u6062\u590d\u7684\u52a8\u7ebf<\/h2>\n<p>\u6211\u4eec\u7684\u6c5f\u5357\u9662\u8bbe\u5728UHC\u96c6\u56e2\u65d7\u4e0b\u9152\u5e97UH FLAT 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