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of Cosmetic Dermatology\u300b\u4e0a\u7684\u7cfb\u7edf\u6027\u6587\u732e\u56de\u987e\u4e0e\u7efc\u5408\u5206\u6790\uff0c\u53ea\u7eb3\u5165\u4e86\u5c06HA\u6ce8\u5165\u771f\u76ae\u5c42\u3001\u5e76\u8bbe\u6709\u751f\u7406\u76d0\u6c34\u3001\u5b89\u6170\u5242\u6216\u4e0d\u5904\u7406\u5bf9\u7167\u7ec4\u7684\u968f\u673a\u4e34\u5e8a\u8bd5\u9a8c\u3002\u7ed3\u679c\u663e\u793a\uff0cHA\u6ce8\u5c04\u7ec4\u7684\u6c34\u5206\u5ea6\u4e0e\u5149\u6cfd\u5ea6\u90fd\u6709\u663e\u8457\u6539\u5584\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u7d27\u81f4\u5ea6\u4e0e\u9ed1\u8272\u7d20\u6307\u6570\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\u6ca1\u6709\u663e\u8457\u5dee\u5f02\uff0c\u4f5c\u8005\u4e5f\u5728\u7ed3\u8bba\u4e2d\u6307\u51fa\uff0c\u8981\u786e\u5b9a\u8fd9\u90e8\u5206\u6548\u679c\u8fd8\u9700\u8981\u66f4\u591a\u7814\u7a76\u3002<\/p>\n<p>\u4e5f\u6709\u5355\u9879\u7814\u7a76\u62a5\u544a\u4e86\u7d27\u81f4\u5ea6\u7684\u6539\u5584\u3002\u6536\u5f55\u4e8e\u7f8e\u56fd\u56fd\u7acb\u533b\u5b66\u56fe\u4e66\u9986PMC\u7684\u4e00\u9879\u4e2d\u56fd\u591a\u4e2d\u5fc3\u968f\u673a\u5bf9\u7167\u7814\u7a76\u4e2d\uff0c\u5171456\u4eba\u53c2\u4e0e\u3001439\u4eba\u5b8c\u6210\u7814\u7a76\u3002\u6cbb\u7597\u7ec4\u6bcf\u9694\u4e00\u4e2a\u6708\u6ce8\u5c04\u4e00\u6b21\u590d\u5408\u900f\u660e\u8d28\u9178\u94a0\u6eb6\u6db2\uff0c\u5171\u4e09\u6b21\u3002\u5bf9\u7167\u7ec4\u4e0d\u63a5\u53d7\u4efb\u4f55\u5904\u7406\u3002\u6cbb\u7597\u7ec4\u7684\u6c34\u5206\u5ea6\u4e0e\u7d27\u81f4\u5ea6\u6539\u5584\uff0c\u5728\u6700\u540e\u4e00\u6b21\u6ce8\u5c04\u540e\u7ef4\u6301\u5230\u7b2c\u4e09\u4e2a\u6708\u3002\u4e0d\u826f\u53cd\u5e94\u53d1\u751f\u7387\u4e3a1.67%\uff0c\u672a\u51fa\u73b0\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\u3002\u4e0d\u8fc7\u8fd9\u9879\u7814\u7a76\u7684\u5bf9\u7167\u7ec4\u662f\u4e0d\u5904\u7406\u800c\u975e\u5b89\u6170\u5242\uff0c\u4f7f\u7528\u7684\u4e5f\u662f\u5355\u4e00\u7684\u590d\u5408\u5236\u5242\uff0c\u56e0\u6b64\u4e0d\u80fd\u628a\u8fd9\u4e2a\u7ed3\u679c\u76f4\u63a5\u5957\u7528\u5230\u6240\u6709\u6c34\u5149\u9488\u4ea7\u54c1\u4e0a\u3002<\/p>\n<p>\u6211\u5bf9\u8fd9\u4e2a\u7ed3\u679c\u7684\u7406\u89e3\u662f\u8fd9\u6837\u7684\u3002\u5982\u679c\u4e3b\u8981\u56f0\u6270\u662f\u76ae\u80a4\u5e72\u71e5\u3001\u7f3a\u4e4f\u5149\u6cfd\u3001\u770b\u8d77\u6765\u6697\u6c89\uff0cHA\u6c34\u5149\u9488\u662f\u76ee\u524d\u6d4b\u91cf\u8bc1\u636e\u6bd4\u8f83\u543b\u5408\u7684\u5019\u9009\u3002\u5982\u679c\u671f\u5f85\u7684\u4e3b\u8981\u662f\u7d27\u81f4\u6216\u63d0\u5347\u6548\u679c\uff0c\u4ece\u7efc\u5408\u5206\u6790\u7684\u5c42\u9762\u770b\uff0c\u8fd9\u90e8\u5206\u6548\u679c\u5c1a\u672a\u5f97\u5230\u786e\u8ba4\uff0c\u4e86\u89e3\u8fd9\u4e00\u70b9\u540e\u518d\u51b3\u5b9a\u4f1a\u6bd4\u8f83\u7a33\u59a5\u3002<\/p>\n<h2>\u5a74\u513f\u9488\uff08PN\u00b7PDRN\uff09\uff1a\u6709\u5bf9\u6bd4\u7814\u7a76\uff0c\u4f46\u89c4\u6a21\u8f83\u5c0f<\/h2>\n<p>\u628aPN\u4e0eHA\u76f4\u63a5\u6bd4\u8f83\u7684\u7814\u7a76\u91cc\uff0cYe Jin Lee\u7b49\u4eba2022\u5e74\u53d1\u8868\u5728\u300aJournal of Dermatological Treatment\u300b\u4e0a\u7684\u968f\u673a\u53cc\u76f2\u5206\u8138\u8bd5\u9a8c\u6bd4\u8f83\u660e\u786e\u3002\u7814\u7a76\u4e3a27\u540d\u53d7\u8bd5\u8005\u8fdb\u884c\u5206\u8138\u6bd4\u8f83\uff1a\u4e00\u4fa7\u773c\u5468\u6ce8\u5c04PN\u586b\u5145\u5242\uff1b\u53e6\u4e00\u4fa7\u6ce8\u5c04\u975e\u4ea4\u8054HA\u586b\u5145\u5242\u3002\u7597\u7a0b\u4e3a\u6bcf\u4e24\u5468\u4e00\u6b21\uff0c\u5171\u4e09\u6b21\u3002\u89c6\u89c9\u6a21\u62df\u8bc4\u5206\uff08VAS\uff09\u4e0e\u6574\u4f53\u7f8e\u5b66\u6539\u5584\u8bc4\u5206\uff08GAIS\uff09\u4e24\u7ec4\u4e4b\u95f4\u6ca1\u6709\u663e\u8457\u5dee\u5f02\u3002\u5f39\u6027\u4e0e\u6c34\u5206\u6539\u5584\u7387\u5728\u4e24\u7ec4\u4e2d\u90fd\u968f\u65f6\u95f4\u4e0b\u964d\uff0c\u4f46PN\u4e00\u4fa7\u66f4\u9ad8\uff1b\u76ae\u80a4\u808c\u7406\u7c97\u7cd9\u5ea6\u4e0e\u6bdb\u5b54\u4f53\u79ef\u7684\u6539\u5584\u7387\u4e5f\u662fPN\u4e00\u4fa7\u66f4\u9ad8\u3002\u771f\u76ae\u5bc6\u5ea6\u7684\u6539\u5584\u7387\u4e24\u7ec4\u4e4b\u95f4\u6ca1\u6709\u663e\u8457\u5dee\u5f02\u3002\u8fd9\u4e2a\u7ed3\u679c\u9700\u8981\u653e\u5728\u773c\u5468\u90e8\u4f4d\u3001\u5c0f\u89c4\u6a21\u7814\u7a76\u7684\u524d\u63d0\u4e0b\u7406\u89e3\u3002<\/p>\n<p>\u8bc1\u636e\u7684\u6574\u4f53\u89c4\u6a21\u4e5f\u9700\u8981\u4e00\u8d77\u770b\u3002\u6536\u5f55\u4e8ePMC\u7684\u4e00\u7bc7PN\u00b7PDRN\u968f\u673a\u4e34\u5e8a\u8bd5\u9a8c\u7cfb\u7edf\u6027\u6587\u732e\u56de\u987e\uff0c\u5408\u5e76\u4e86\u76ae\u80a4\u518d\u751f\u3001\u4f24\u75a4\u4e0e\u4f24\u53e3\u6108\u5408\u76f8\u5173\u76847\u9879\u7814\u7a76\uff0c\u5171183\u4eba\uff0c\u5355\u9879\u7814\u7a76\u7684\u5206\u6790\u4eba\u6570\u572810\u523042\u4eba\u4e4b\u95f4\uff0c\u968f\u8bbf\u65f6\u95f4\u4ece2\u5468\u52306\u4e2a\u6708\u4e0d\u7b49\u3002\u76f8\u6bd4HA\u6c34\u5149\u7684\u7814\u7a76\u6570\u91cf\u4e0e\u4eba\u6570\uff0c\u8fd9\u4e2a\u89c4\u6a21\u660e\u663e\u66f4\u5c0f\u3002<\/p>\n<p>\u65bd\u672f\u65f6\u7684\u611f\u53d7\u4e5f\u6709\u5dee\u5f02\u30022025\u5e74\u53d1\u8868\u5728\u300aAesthetic Plastic Surgery\u300b\u4e0a\u7684\u4e00\u9879\u968f\u673a\u5206\u8138\u7814\u7a76\u7684\u4f5c\u8005\u5199\u9053\uff0cPN\u586b\u5145\u5242\u56e0\u5176\u518d\u751f\u7279\u6027\u88ab\u5e7f\u6cdb\u4f7f\u7528\uff0c\u4f46\u6ce8\u5c04\u65f6\u7684\u75bc\u75db\u662f\u4e3b\u8981\u7f3a\u70b9\u3002\u4e3d\u73e0\u5170\u9ed1\u76d2\u3001\u4e3d\u73e0\u5170\u7ea2\u76d2\u7b49\u4e3d\u73e0\u5170\u7cfb\u5217\u4ea7\u54c1\u5c5e\u4e8ePN\u5236\u5242\uff0c\u75bc\u75db\u7ba1\u7406\u65b9\u5f0f\u4e5f\u5efa\u8bae\u5728\u9762\u8bca\u65f6\u4e00\u5e76\u786e\u8ba4\u3002<\/p>\n<h2>\u5916\u6ccc\u4f53\uff1a\u8c08\u6548\u679c\u4e4b\u524d\uff0c\u5148\u786e\u8ba4\u76d1\u7ba1\u7c7b\u522b<\/h2>\n<p>\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u57282019\u5e7412\u67086\u65e5\u7684\u516c\u544a\u4e2d\u6307\u51fa\uff0c\u5185\u5e03\u62c9\u65af\u52a0\u5dde\u6709\u591a\u540d\u60a3\u8005\u5728\u63a5\u53d7\u5ba3\u79f0\u542b\u6709\u5916\u6ccc\u4f53\u7684\u672a\u83b7\u6279\u4ea7\u54c1\u540e\uff0c\u51fa\u73b0\u4e86\u591a\u8d77\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\u62a5\u544a\u3002\u540c\u4e00\u4efd\u516c\u544a\u8bf4\u660e\uff0c\u76ee\u524d\u6ca1\u6709\u83b7\u5f97\u6279\u51c6\u7684\u5916\u6ccc\u4f53\u4ea7\u54c1\uff0c\u82e5\u7528\u4e8e\u6cbb\u7597\u75be\u75c5\u6216\u75c5\u75c7\uff0c\u5916\u6ccc\u4f53\u9700\u6309\u836f\u54c1\u6216\u751f\u7269\u5236\u54c1\u7684\u6807\u51c6\u63a5\u53d7\u4e0a\u5e02\u524d\u5ba1\u67e5\u4e0e\u6279\u51c6\u3002FDA\u7684\u518d\u751f\u533b\u5b66\u6d88\u8d39\u8005\u4fe1\u606f\u9875\u9762\u4e5f\u5199\u660e\uff0c\u5916\u6ccc\u4f53\u5728\u5185\u7684\u672a\u83b7\u6279\u518d\u751f\u533b\u5b66\u4ea7\u54c1\uff0c\u66fe\u6536\u5230\u5931\u660e\u3001\u80bf\u7624\u5f62\u6210\u3001\u611f\u67d3\u7b49\u62a5\u544a\u3002<\/p>\n<p>\u97e9\u56fd\u56fd\u5185\u4e5f\u51fa\u73b0\u8fc7\u7c7b\u4f3c\u7684\u95ee\u9898\u30022022\u5e74\u4fdd\u5065\u798f\u7949\u90e8\u56fd\u653f\u76d1\u67e5\u4e2d\uff0c\u56fd\u4f1a\u4fdd\u5065\u798f\u7949\u59d4\u5458\u4f1a\u5d14\u60e0\u82f1\u8bae\u5458\u6307\u51fa\uff0c\u6ce8\u5c04\u5165\u771f\u76ae\u5c42\u5c5e\u4e8e\u533b\u7597\u884c\u4e3a\uff0c\u4f46\u5916\u6ccc\u4f53\u4ea7\u54c1\u5374\u4ee5\u5316\u5986\u54c1\u540d\u4e49\u5728\u98df\u54c1\u533b\u836f\u54c1\u5b89\u5168\u5904\u767b\u8bb0\u3002\u636e\u5f53\u65f6\u7684\u62a5\u9053\uff0c\u5316\u5986\u54c1\u4e0d\u50cf\u836f\u54c1\u90a3\u6837\u9700\u8981\u54c1\u76ee\u8bb8\u53ef\u7a0b\u5e8f\u4e0e\u65e0\u83cc\u5236\u9020\u6807\u51c6\u3002\u6ce8\u5c04\u540e\u7684\u5f71\u54cd\u4e5f\u5c1a\u672a\u5f97\u5230\u786e\u8ba4\uff0c\u5e76\u5df2\u6536\u5230\u4f24\u75a4\u3001\u53d1\u7ea2\u7b49\u526f\u4f5c\u7528\u7533\u8bc9\u6848\u4f8b\u3002\u5927\u97e9\u76ae\u80a4\u79d1\u533b\u5e08\u4f1a\u540c\u5e74\u4e5f\u5411\u4f1a\u5458\u53d1\u51fa\u4e86\u63d0\u9192\u6ce8\u610f\u7684\u901a\u77e5\u3002<\/p>\n<p>\u76d1\u7ba1\u60c5\u51b5\u4f1a\u56e0\u4ea7\u54c1\u4e0e\u65f6\u95f4\u70b9\u800c\u53d8\u5316\u3002\u6240\u4ee5\u5982\u679c\u6b63\u5728\u8003\u8651\u4f7f\u7528\u5916\u6ccc\u4f53\uff0c\u6211\u5efa\u8bae\u5728\u9762\u8bca\u65f6\u76f4\u63a5\u786e\u8ba4\u4ea7\u54c1\u540d\u79f0\u3001\u5b83\u5c5e\u4e8e\u836f\u54c1\u8fd8\u662f\u5316\u5986\u54c1\u3001\u662f\u6d82\u62b9\u65b9\u5f0f\u8fd8\u662f\u6ce8\u5c04\u65b9\u5f0f\u3002\u5224\u65ad\u73bb\u7483\u808c\u6548\u679c\uff0c\u5e94\u8be5\u5728\u8fd9\u4e00\u6b65\u4e4b\u540e\u518d\u8c08\u3002<\/p>\n<h2>\u6309\u76ae\u80a4\u56f0\u6270\u7f29\u5c0f\u5019\u9009\u8303\u56f4\u7684\u987a\u5e8f<\/h2>\n<p>\u73bb\u7483\u808c\u867d\u7136\u662f\u540c\u4e00\u4e2a\u76ee\u6807\uff0c\u4f46\u4e0d\u540c\u7684\u76ae\u80a4\u72b6\u51b5\uff0c\u51fa\u53d1\u70b9\u5e76\u4e0d\u76f8\u540c\u3002\u6309\u7814\u7a76\u6d4b\u91cf\u7684\u9879\u76ee\u6574\u7406\u5982\u4e0b\uff1a<\/p>\n<ol>\n<li><strong>\u76ae\u80a4\u5e72\u71e5\u6697\u6c89\u3001\u7f3a\u4e4f\u5149\u6cfd<\/strong>\uff1aHA\u6c34\u5149\u9488\u662f\u53ef\u4ee5\u4f18\u5148\u8003\u8651\u7684\u5019\u9009\uff0c\u7efc\u5408\u5206\u6790\u4e2d\u786e\u8ba4\u6709\u6539\u5584\u7684\u9879\u76ee\u6b63\u662f\u6c34\u5206\u5ea6\u4e0e\u5149\u6cfd\u5ea6\u3002<\/li>\n<li><strong>\u76ae\u80a4\u808c\u7406\u7c97\u7cd9\u3001\u773c\u5468\u7ec6\u7eb9\u6216\u6bdb\u5b54\u660e\u663e<\/strong>\uff1a\u53ef\u4ee5\u628aPN\u7cfb\u5217\u4e00\u5e76\u5217\u5165\u5019\u9009\uff0c\u4f46\u4e0eHA\u6bd4\u8f83\u7684\u8bc1\u636e\u4ec5\u9650\u4e8e\u773c\u5468\u90e8\u4f4d\u7684\u5c0f\u89c4\u6a21\u7814\u7a76\u3002<\/li>\n<li><strong>\u4e3b\u8981\u56f0\u6270\u662f\u7d27\u81f4\u6216\u4e0b\u5782<\/strong>\uff1a\u4ee5\u4e0a\u4e09\u8005\u5728\u8fd9\u4e2a\u76ee\u7684\u4e0a\u7684\u8bc1\u636e\u90fd\u4e0d\u7b97\u5145\u5206\u3002\u5982\u679c\u786e\u5b9e\u6709\u4e0b\u5782\u60c5\u51b5\uff0c\u5efa\u8bae\u8fde\u540c\u63d0\u5347\u7c7b\u9879\u76ee\u4e00\u8d77\u63a5\u53d7\u8bca\u65ad\u3002<\/li>\n<li><strong>\u88ab\u5efa\u8bae\u4f7f\u7528\u5916\u6ccc\u4f53<\/strong>\uff1a\u6bd4\u8d77\u6548\u679c\u6bd4\u8f83\uff0c\u5148\u786e\u8ba4\u4ea7\u54c1\u7684\u76d1\u7ba1\u7c7b\u522b\u4e0e\u7ed9\u836f\u65b9\u5f0f\u3002<\/li>\n<\/ol>\n<p>\u5982\u679c\u5728\u9996\u5c14\u505c\u7559\u65f6\u95f4\u8f83\u77ed\uff0c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