Rejuran vs Juvelook: Gangnam Dermatologist Explains

Skin boosters are among the most popular aesthetic treatments available in Korea for people looking to improve their skin. With dermatology clinics in Korea offering a wide range of skin booster treatments, many people find it difficult to decide which option is right for them. In this article, we’ll take a closer look at the features and differences between Rejuran and Juvelook, two of the most popular skin boosters, to help you choose the treatment that best suits your skin condition.

What is a Skin Booster?

A skin booster is a treatment that delivers active ingredients directly into the dermis using fine needles. Rather than a superficial treatment, it works by promoting hydration and stimulating collagen production from within.Recently, a variety of skin booster products, including Rejuran and Juvelook, have been introduced, and each product differs in its key ingredients and mechanism of action.

Key Characteristics and Effects of Rejuran

The main ingredient in Rejuran is polynucleotides (PN), which are salmon-derived DNA extracts. This ingredient was initially developed in Korea for burn patients and individuals with severe inflammatory skin conditions, and is known for its strong anti-inflammatory properties.Rejuran helps reduce inflammation and may improve skin redness, itching, and dryness.

Additionally, hyaluronic acid, which is commonly included in all skin boosters, is also contained in Rejuran, allowing you to expect hydration and improved moisture retention. A distinctive feature is that you can notice improvements in skin elasticity and radiance relatively quickly—right after the procedure, the next day, and within a week.

• Active Ingredient: Salmon DNA extract (polynucleotide)
• Key Effect: Anti-inflammatory, reduces redness and dryness
• Time to Results: Noticeable improvements immediately after treatment
• Recommended For: Those with atopic dermatitis, sensitive skin, or seasonal dryness

Characteristics of Juvelook and Its Collagen Generation Mechanism

The main ingredient in Juvelook is polylactic acid, a polymer of lactic acid. These fine particles act as seeds for collagen formation in the dermis layer of the skin. You may not notice immediate changes after the procedure, but gradual improvements in skin texture can be expected as collagen production increases over time. Visible results typically develop over 2 weeks to 2 months, and may continue to improve even beyond that period.

Since the polylactic acid component in Juvelook eventually breaks down into water, the degradation process continuously generates moisture. Therefore, the product can provide long-lasting hydration effects as it gradually breaks down over 2 months to 1 year following the procedure. For this reason, it is highly effective for improving uneven acne scars and enlarged pores.

• Active Ingredient: Polylactic acid (polymer of lactic acid)
• Primary Effect: Promotes collagen generation, provides long-term hydration
• Time to Results: Gradual improvements begin after 2 weeks
• Recommended For: Acne scars, enlarged pores, uneven skin texture

Pain Comparison: Rejuran vs Juvelook

One of the most common questions people ask when considering skin booster treatments is about pain. In general, Juvelook tends to cause less discomfort than Rejuran. However, the level of discomfort can vary depending on the clinic’s anesthesia protocol and how the product is prepared. When an experienced medical professional appropriately incorporates an anesthetic into the mixture, the discomfort associated with Juvelook can be further reduced.

Many clinics consider the order of procedures important when administering both products simultaneously. If Juvelook is injected first and then Rejuran is applied to the same area, pain can be significantly reduced. Therefore, if you are sensitive to pain, we recommend informing your medical professionals during the consultation and requesting a procedure method tailored to your individual pain sensitivity.

Treatment Selection Guide Based on Skin Condition

For Sensitive Skin, Redness, or Seasonal Dryness

Rejuran is recommended for those with atopic dermatitis or those who experience severe flaking and redness during seasonal changes. The anti-inflammatory effects of the salmon DNA extract can help calm skin irritation, and hydration can help improve dryness.

For Acne Scar and Pore Improvement

Juvelook is recommended for those with uneven skin texture and enlarged pores caused by acne. By stimulating collagen production, it may help improve overall skin texture. With a series of treatments, you can expect gradual, natural-looking improvements.

For Those Seeking Both Immediate and Long-Term Results

Many clinics combine Rejuran and Juvelook in the same treatment session. In this approach, Rejuran provides visible improvements early on, while Juvelook’s collagen-stimulating effects gradually build over time, delivering sustained, long-term skin improvement.

Post-Treatment Side Effects and Precautions

Since skin boosters use injection needles, common injection-related side effects such as bruising, swelling, and bleeding may occur. Additionally, an “embossing effect” where the skin appears bumpy may appear for 1-2 days immediately after treatment. This is a normal response and will naturally improve over time.

If you have an important event or photo shoot scheduled, be sure to inform your medical professional during the consultation. Experienced medical professionals can minimize the embossing effect by adjusting the injection depth. They can also flexibly modify the treatment approach based on your skin condition and schedule.

Manual Injection vs Machine Injection

Skin boosters can be administered using two methods: manual injection and machine injection. The advantage of manual injection is that it is completed very quickly. For experienced medical professionals, the procedure can be completed within 1-2 minutes, making manual injection ideal if you want to finish your treatment in minimal time. Additionally, it minimizes waste so that precious medication is not lost.

The advantage of machine injection is that it causes less pain. However, the procedure takes approximately 7-10 minutes, so while the discomfort is reduced, the treatment duration is longer. Additionally, the medication can be distributed more homogeneously and thoroughly. We recommend experiencing both manual and machine injection methods before choosing the approach that works best for you.

Conclusion: Professional Consultation Is Key

Rejuran and Juvelook each have their own advantages and characteristics, and there is no single “better” treatment option. What matters is receiving customized treatment by comprehensively considering your current skin condition, desired improvement goals, pain sensitivity, and schedule.

Medical professionals at excellent dermatology clinics do not simply recommend just one procedure. Rather, they conduct a precise diagnosis of your skin condition and propose the optimal treatment method and product combination for you. They also apply various expertise to minimize pain, including anesthesia methods, needle selection, and the order of procedures.

If you are considering a skin booster treatment, information found online alone may not be sufficient. We strongly recommend scheduling a personal consultation with a specialist dermatologist to find the treatment method best suited to your skin. An honest consultation with experienced medical professionals is the first step toward a successful procedure.

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Source : https://youtu.be/5BmtHePyIuQ

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[Dr. Kim Yeon-Jin, Medical Director, UH CELL Clinic Gangnam] Miss Universe Judge | Former Medical Director, Dr. Petit Clinic Gangnam

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